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C 200 auto – Welcom to truegenix lab solution

Welcom to truegenix lab solution

C 200 auto

C 200 auto

The C 200 auto package allows operating the C 200 with a completely automated water cycle. This results in ease of handling and saves valuable time especially for laboratories with a low number of analyses. The water circulates in a closed loop and is kept at a constant temperature by using a recirculating chiller. This leads to shorter preparation time for each experiment and even better reproducible results.

The semi-automated and conforming to standards combustion calorimeter determines the gross calorific value of liquid and solid samples. So far it has mainly been used for teaching and training purposes at technical schools and universities. Due to the automated water handling it is now also suitable for industrial laboratories with low number of analyses.

Four different operation modes enable the user to control the measuring times according to individual requirements:
Isoperibol: approx: 17 min.
Dynamic : approx. 8 min
Manual : approx. 17 min (depends on the operator)
Time controlled : 14 min

Measurements are possible according to e.g. DIN 51900, ISO 1928, ASTM D240, ASTM D4809, ASTM D5865, ASTM D1989, ASTM D5468, ASTM E711.

The software C 6040 Calwin controls the unit and monitors the measurement of the samples. Additionally, collected data can be exported to e.g. Excel, Word, SQL and LIMS for further analysis. It is possible to operate several calorimeters with one PC. A PC is not part of the scope of delivery and needs to be provided by the operator. Calwin is sold separately.

Scope of delivery
  • C 200 Measuring cell
  • C 5010 Decomposition vessel
  • C 200.RC Set of hoses
  • RC 2 basic
  • C 248 Oxygen filling station
  • Ignation adapter
  • Water emptying hose
Measuring range max.40000 J
Measuring mode dynamic 25°Cyes
Measuring mode isoperibol 25°Cyes
Measuring time dynamic approx.8 min
Measuring time isoperibol approx.17 min
Reproducibility dynamic (1g benzoic acid NBS39i)0.1 %RSD
Reproducibility isoperibol (1g benzoic acid NBS39i)0.1 %RSD
Working temperature max.25 °C
Temperature measurement resolution0.0001 K
Cooling medium permissible operating pressure2 bar
Cooling mediumtap water
Type of coolingflow
ChillerRC 2 basic
Rec. flow rate at 18°C60 l/h
Oxygen operating pressure max.40 bar
Interface printerCentronix
Interface PCRS232
Decomposition vessel C 5010yes
Works according to DIN 51900yes
Works according to DIN EN ISO 1716yes
Works according to DIN EN ISO 18125yes
Works according to DIN EN 15400yes
Works according to DIN CEN TS 14918yes
Works according to DIN CEN/TS 16023yes
Works according to DIN SPEC 19524yes
Works according to ASTM D240yes
Works according to ASTM D4809yes
Works according to ASTM D5468yes
Works according to ASTM D5865yes
Works according to ISO 1928yes
Works according to GOST Certifiedyes
Dimensions (W x H x D)400 x 400 x 400 mm
Weight64.2 kg
Permissible ambient temperature20 – 25 °C
Permissible relative humidity80 %
Protection class according to DIN EN 60529IP 20
RS 232 interfaceyes
Voltage100 – 240 V
Frequency50/60 Hz
Power input120 W

 

Control and monitoring
The intuitive software allows easy control and monitoring of the bioprocess and associated parameters via a 10.4-inch tablet. Users can select from batch, fed-batch, and perfusion/continuous operating modes, catering to various cell culture techniques. The innovative Chaotic Mixing function enables efficient and homogeneous mixing when required. The control software provides clear calibration management, real-time data visualization, and complete process documentation, ensuring compliance with FDA CFR Part 11 requirements (optional).

Gas supply
Precise and adjustable gassing is achieved through four individual built-in mass flow controllers for four each separate gas line (N2, O2, air and CO2), enabling flow rates of 0.01 – 2 L / min. tailored to cell growth requirements. By using the integrated and freely customizable cascade control system, each gas flow can be automatically adjusted by the software at any time according to the ambient conditions in order to maintain the target parameters.

Liquid supply
Four integrated Watson-Marlow pumps with adjustable direction and speed offer highest precision and versatility in pumping in and out acid, base, anti-foam agents and feeding solutions for mammalian cell culture media management.

Sensors
HABITAT Bioreactor comes equipped with latest technology sensors to precisely monitor and control critical bioprocess parameters. The following sensors are included in our standard sales vessel packages:
• pH
• DO (dissolved oxygen)
• temperature
• filling level
• foam
Optional sensors: CO2, Conductivity, Turbidity, Viable cell mass, Redox, Off-gas analysis and more.

PID temperature control
The integrated PID control ensures precise temperature regulation at all times, regardless of vessel type (single-wall or double-wall) or fill level. Single-wall glass vessels can be heated with a heating blanket, allowing for accurate temperature settings above room temperature. With the optional use of a cooling finger, it is also possible to achieve temperatures below room temperature. For double-wall vessels, in combination with an IKA thermostat, the temperature range can be freely adjusted between 5-80°C, independent of room conditions or heat generated by the culture itself.

All features at a glance
• compact, space-saving design, dimensions: 223 x 402 x 450 mm (WxDxH)
• latest technology sensors for better insights and more control
• large screen tablet for easy operation (10.4 inch)
• intuitive, easy-to-use control software that provides simple initial setup and intuitive user assistance throughout the process
• four integrated Watson-Marlow pumps
• high precision motor speed control
• cross platform connectivity: USB, PC, RS232, OPC-UA, ethernet, external signal input, external pump, single-use unit, thermostat
• data storage
• four built-in mass flow controllers for gas supply: N2, O2, air, and CO2
• status LED display: direct error display by indicator light

Note: Only a control tower and the separately available vessel package make up a functional unit.

Scope of delivery

  • HABITAT cell S099
  • Tablet with software for bioreactor
ControllerCell Growth
Operating modetimer, continuous and program operation
DisplayTablet PC
Operationtouch screen
Data memory size32 GB
Auto restart after power failureyes
Ethernet interfaceyes
Single use reactor interfaceyes
Thermostat interfaceyes
Ext. pump interfaceyes
Gravimetric feedingyes
Exponential feedingyes
Biomass feedingyes, with Excell Sensor
OPC UA interfaceyes
Filter heateryes
LED light panelAccessory
Stirring motoryes
Calibration guide temperatureyes
Calibration guide pHyes
Calibration guide pO2yes
pH – temperature compensationyes
Mode hose fillingyes
Stirrer control modeoff, manual, profile, Cascade-pO2 control, chaotic
Speed range1 – 2200 rpm
Speed deviation >= 100 rpm±2 %
Speed deviation <= 100 rpm±5 rpm
Speed displayTFT
Reversible direction of rotationyes
Timeryes
Timer displayTFT
Time setting range1 – 120 min
Heating blanketyes
Heat output250 W
Heat controlTFT
Temperature controlPID
Working temperature5 – 80 °C
Connection for ext. temperature sensorPT1000
Temperature displayyes
Temperature measuring range0 – 100 °C
Temperature measurement resolution0.1 K
Temperature control accuracy±0.2 °C
Temperature limit min.0 °C
Temperature limit max.110 °C
pH measurementyes
pH control modeoff, auto, profile
pH value displayTFT
pH measuring range0 – 14 pH
pH measurement resolution0.01 pH
Accuracy of pH measurement±0.02 pH
Set resolution pH value0.01 pH
pH control accuracy±0.05 pH
Conncetion for pO2 sensoryes
pO2 control modeoff, manual, auto, profile
Measurement range pO2 min.0 %sat
Measurement range pO2 max.200 %sat
Resolution pO2 measurement0.01 %sat
Accuracy of pO2 measurement±0.3 %sat
pO2 control accuracy0.3 %sat
Exhaust Gas Analyzeryes, with Blue Vary Sensor
OUR,CER,RQ calculationyes, with Blue Vary Sensor
RQ feedingyes, with Blue Vary Sensor
Digital pH sensoryes, with EasyFerm Bio Arc Sensor
Measuring Range min. digital pH0 pH
Measuring Range max. digital pH14 pH
Accuracy digital pH±0.02 pH
Digital DO sensoryes, with OxyFerm FDA Arc
Measuring Range min. digital DO0 %sat
Measuring Range max. digital DO200 %sat
Accuracy digital DO±2 %
Optical DO sensoryes, with VisiFerm RS485-ECS
Measuring Range min. optical DO0 %sat
Measuring Range max. optical DO300 %sat
Accuracy optical DO±1 %
Biomass sensoryes, with CGQ BioR Sensor
Measuring Range min. Biomass0.5 OD
Measuring Range max. Biomass50 OD
Digital Redox / ORP sensoryes, with EasyFerm Plus ORP Arc
Measuring Range min. digital ORP-1500 mV
Measuring Range max. digital ORP1500 mV
Digital biomass sensoryes, with Excell Sensor
Measuring Range min. digital biomass0 AU
Measuring Range max. digital biomass6 AU
Accuracy digital biomass±1 %
Viable Cell Density Sensorsyes, with Incyte Sensor
Measuring Range min. cell density5 x 10^5 cells/mL
Measuring Range max. cell density8 x 10^9 cells/mL
Accuracy cell density±1 %
Gas in connection Air6 mm
Gas out connection Air6 mm
Gas in connection O26 mm
Gas out connection O26 mm
Gas in connection N26 mm
Gas out connection N26 mm
Gas in connection CO26 mm
Gas out connection CO26 mm
Aeration modecontinuous & automatic
Display flowratel/min, cc/min
Input pressure200 – 3000 mbar
Pressure out min.200 mbar
Pressure out max.1000 mbar
Flowrate Air min.10 cc/min
Flowrate Air max.2000 cc/min
Flowrate O2 min.10 cc/min
Flowrate O2 max.2000 cc/min
Flowrate N2 min.10 cc/min
Flowrate N2 max.2000 cc/min
Flowrate CO2 min.10 cc/min
Flowrate CO2 max.2000 cc/min
Measuring and control accuracy of the gas control units±2 % fsr
Peristaltic pumpyes
Numbers of pump heads4
Pump head functionAcid, Base, AntiFoam, Level
Pump headWatson Marlow 114DV
Number of pump tubes4
Number of pump rollers4
Flow rate min.0.3 ml/min
Flow rate max.270 ml/min
Flow rate control accuracy±0.3 ml/min
Pump Speed min.33 rpm
Pump Speed max.400 rpm
Pump reversible direction of rotationyes
Pump speed displayTFT
Inner tube diameter min.0.5 mm
Inner tube diameter max.4.8 mm
Tube outer diamter min.4.1 mm
Tube outer diamter max.8.4 mm
Tube materialSilicone
Tube hardness50 – 60 Shore A
Dimensions (W x H x D)224 x 624 x 405 mm
Weight14 kg
Packing unit1 pcs
Permissible ambient temperature5 – 40 °C
Permissible relative humidity80% (up to 31°C), decreasing linearly to max. 50 (@40°C)
Protection class according to DIN EN 60529IP 20
RS 232 interfaceyes
USB interfaceUSB-B
WiFi Interfaceyes
Voltage100 – 240 V
Frequency50/60 Hz
Power input300 W
Power input max.1100 W
Power input standby10 W
Fuse2x T5.0A 250V
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History

Our Journey Map

Welcom to truegenix lab solution
1997

The Beginnings

Choose a suitable location for your laboratory, considering factors such as accessibility, space requirements, and proximity to potential collaborators.

The Beginnings

Winning a research award is a significant achievement and a testament to your hard work, dedication, and contributions to your field of study.

2003
Welcom to truegenix lab solution
Welcom to truegenix lab solution
2008

Opening New Laboratory

Choose a location that meets the specific needs of your research. Consider factors such as proximity to collaborators, accessibility, and availability necessary utilities & infrastructure.

Updating Equipment

Determine the budget required for updating the equipment. Explore funding options, including grants, institutional support, or collaborations with industry partners.

2016
Welcom to truegenix lab solution